Vertical Basket Centrifuge – Top Discharge

Vertical Basket Centrifuge – Top Discharge


The Vertical Basket Centrifuge with Top Discharge offers simple yet efficient filtration (solid/liquid separation) of fine chemicals or Active Pharmaceutical Ingredients (API).

It is used for products that need a large filtering surface and very frequent product changes, due to its simple operation and cleaning procedures. This is the least closed environment because the unit is opened for product removal, therefore additional measures may need to be taken for containment.

Production Cycle and Design Advantages

Typical Applications

  • Fine chemicals
  • Pharmaceuticals
  • API 


  • Batch filtering centrifuge with product discharge from the top
  • Fixed frame or GMP design available
  • Full inspection of process area and flat basket bottom is possible with GMP design
  • Glove box operation (for high containment) is available
  • Production of chemical and pharmaceutical products from synthesis processes
  • Suitable for products requiring a large filtering surface area
  • Simple operation and cleaning procedures allow for frequent change of production

Discharge Versions

  • ALFA/B: The simplest model with manual cake removal by hand shovel or, for small models, lifting a bag by hand. This model is used mainly for small sizes (filter bag and filter cloth may be used).
  • ALFA/SB: The solids discharge is achieved by lifting the bag up (the most common system). An optional system can be used for “automatic” bag lifting.
  • ALFA/SB CA: The solids are discharged by a knife and evacuated via a pneumatic system (vacuum). The system is only useable with easy products that can be pneumatically transported and dedicated productions. The advantage is to avoid contact between operator and the product and between the product and the external environment.

Control Options

  • Complete PLC controls with touch screen interface
  • Switch between automatic, semiautomatic, and manual operation
  • Variable frequency drive (VFD) speed control
  • ATEX (Europe) electrical enclosures or NEC (North America)
  • Optional instrumentation integrated into the control system including oxygen monitoring, temperature, pressure, liquid feed flow, N2 purge flow, effluent particle detection and fluid clarity


  • The centrifuge should be cleaned at every change of product to avoid cross contamination between campaign productions. The fully automated centrifuge cleaning system is composed of 2 main stages: Washing Machine Effect and cleaning with spray balls, which can be alternated to achieve maximum cleaning and to optimize the consumption of the cleaning liquid.
  • C.I.P. (Clean-In-Place) avoids cross contamination at every change of production
  • Both options for the Washing Machine Effect cycle and spray balls are available

Machine Characteristics

  • Small footprint
  • Filter options:
    • Polypropylene or other fabrics of various micron sizes
    • Sintered metal screen for microfiltration (down to 2 microns)
  • Inertia base installation with visco dampers
  • Optional cake detector for automatic loading without operator intervention and cake thickness monitoring
  • System for dissolving the cake “in situ” to avoid typical solids discharge
  • For smaller machines, a glove box can be provided for high containment
  • Construction materials
    • Parts in contact with the product: all stainless steels and special alloys are available, such as AISI 316L, AISI 904L, hastelloy, monel, alloy 59, 254 SMO, nickel, titanium, SAF 2205
    • Surface coating option: Halar (ECTFE),
    • Elastomers: antistatic and FDA certified, Teflon ETFE, and hard rubber

Technical Services

  • Field service and technical support available
  • Mechanical and electrical parts
  • Process control and maintenance manuals
  • Certifications and construction documentation
  • Mechanical and electrical upgrades

Standard Sizes and Technical Data

Centrifuge model: ALFA
Basket Diameter
Basket Length
Filtering Surface
Cake Volume
Max Load
Max Speed
G Factor
Centrifuge Weight
350/260 350 260 0.28 15 20 2800 1532 900
550/350 550 350 0.6 40 50 2550 2000 1200
630/400 630 400 0.8 63 80 1900 1250 1500
800/400 800 400 1.00 100 125 1500 1000 2900
1000/500 1000 500 1.57 200 250 1200 800 4000
1250/500 1250 500 1.96 315 400 1000 700 5300
1250/630 1250 630 2.47 400 500 1000 700 6000
1250/800 1250 800 3.14 500 625 1000 700 6500
1600/800 1600 800 4.02 800 1000 850 646 8000

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