Vertical Basket Centrifuge – Bottom Discharge (Chemical & Pharma) (TM/S-IV)
Vertical Basket Centrifuge – Bottom Discharge (Chemical & Pharma) (TM/S-IV)

The Vertical Basket Centrifuge with Bottom Discharge is for the efficient solid/liquid separation of chemicals and Active Pharmaceutical Ingredients (API) in a single sealed environment.
Bottom Discharge is an extremely versatile centrifugal solution. This model has the:
- largest cake volume
- most filter area available, up to 7m2 in one machine
- most economical option
- simplest design
Production Cycle and Design Advantages
Typical Applications
- Pharmaceutical and fine chemical products
- Active Product Ingredients (APIs)
- Antibiotics
- Pharmaceutical Intermediate Products
- Bulk and generic pharmaceuticals
- High Potent Active Product Ingredients (HPAPI)
- Fine chemical products
- Agrochemicals
- Food product
Highlights
- Vertical basket with top load and with bottom discharge
- Automatic discharge with scraper knife
- Fixed frame or GMP design available
- Full inspection of process area is possible with the GMP design, and meets pharmaceutical industry requirements
- Production of bulk pharmaceutical products from synthesis processes
- Suitable for products requiring a wide filtering surface
- No contact between the operator and the product during operation makes it suitable for toxic and flammable products
- The centrifuge may be kept under a constant inert atmosphere
- Rotating distributor for feeding and washing allows for uniform cake distribution and avoids vibrations
Discharge
- Automatic Discharge by scraper knife movement up and down, radially by steps, or total peel off (vertical peeler)
- Nitrogen nozzles to remove heel cake internally
Control Options
- Complete PLC controls with touch screen interface
- Switch between automatic, semiautomatic, and manual operation
- Variable frequency drive (VFD) speed control for the basket
- Knife and cover opening are hydraulically operated
- ATEX (Europe) electrical enclosures or NEC (North America)
- Optional instrumentation integrated into the control system including oxygen monitoring, temperature, pressure, liquid feed flow, N2 purge flow, effluent particle detection and fluid clarity
Cleaning
- Its highly effective C.I.P. system (Clean-in- Place) uses a Washing Machine Effect and spray balls.
- Multipurpose application: The C.I.P. system avoids cross-contamination between products from one campaign production to another, which makes the machine suitable for multi-purpose applications
- C.I.P.
- The centrifuge should be cleaned at every change of product to avoid cross-contamination between campaign productions. The fully automated centrifuge cleaning system is composed of 2 main stages: Washing Machine Effect and cleaning with spray balls, which can be alternated to achieve maximum cleaning and to optimize the consumption of the cleaning liquid.
- Washing Machine Effect (optional)
- The centrifuge is filled with the washing liquid up to a predetermined height and is put in rotation. During the automatic washing sequence, the basket rotates both clockwise and counterclockwise. The knife goes in and out so that the washing liquid reaches all points of the process area, including the discharge chute.
Machine Characteristics
- Easily replaceable filter cloth is mounted in the basket by rings
- High level surface finishes for the process areas; mirror-like or electrochemical polishing are available
- Relatively small footprint – limited horizontal space required
- Inertia base installation with visco dampers
- Construction materials:
- Parts in contact with the product: all stainless steels and special alloys are available, such as AISI 316L, AISI 904L, hastelloy, monel, alloy 59, 254 SMO, nickel, titanium, SAF 2205.
- Surface coating option: Halar (ECTFE)
- Elastomers: antistatic and FDA certified, Teflon ETFE, and hard rubber
Technical Services
- Field service and technical support available
- Mechanical and electrical parts
- Process control and maintenance manuals
- FDA qualification documentation and book to complete the plant
- Certifications and construction documentation
- Mechanical and electrical upgrades
Chemical Applications
Pharma Applications
Standard Sizes and Technical Data
Centrifuge model: TM Unit |
Basket Diameter mm |
Basket Length mm |
Filtering Surface m2 |
Cake Volume liters |
Max Load kg |
Max Speed RPM |
G Factor xg |
Centrifuge Weight kg |
800/250 | 800 | 250 | 0.63 | 63 | 79 | 1650 | 1216 | 1500 |
800/400 | 800 | 400 | 1.01 | 100 | 125 | 1500 | 1006 | 2000 |
1000/500 | 1000 | 500 | 1.57 | 200 | 250 | 1200 | 805 | 3800 |
1000/630 | 1000 | 630 | 1.98 | 250 | 312 | 1200 | 805 | 4250 |
1250/700 | 1250 | 700 | 2.75 | 400 | 500 | 1000 | 700 | 6400 |
1250/800 | 1250 | 800 | 3.14 | 500 | 625 | 1000 | 700 | 6700 |
1600/800 | 1600 | 800 | 4.02 | 820 | 1025 | 900 | 724 | 12000 |
1600/1000 | 1600 | 1000 | 5.03 | 1025 | 1280 | 900 | 724 | 13000 |
1700/1190 | 1700 | 1190 | 6.3 | 1377 | 1721 | 850 | 686 | 14500 |
1850/1250 | 1850 | 1250 | 7.26 | 1710 | 2140 | 800 | 643 | 16500 |