Vertical Basket Centrifuge – Bottom Discharge (Chemical & Pharma) (TM/S-IV)

Wave

Vertical Basket Centrifuge – Bottom Discharge (Chemical & Pharma) (TM/S-IV)

Alfa-aperta-da-scontornare

The Vertical Basket Centrifuge with Bottom Discharge is for the efficient solids/liquids separation of chemicals and Active Pharmaceutical Ingredients (API) in a single sealed environment.

Bottom Discharge is an extremely versatile centrifugal solution. This model has the:

  • largest cake volume
  • most filter area available, up to 7m2 in one machine
  • most economical option
  • simplest design

Production Cycle and Design Advantages

Typical Applications

  • Pharmaceutical and fine chemical products
  • Active Product Ingredients (APIs)
  • Antibiotics
  • Pharmaceutical Intermediate Products
  • Bulk and generic pharmaceuticals
  • High Potent Active Product Ingredients (HPAPI)
  • Fine chemical products
  • Agrochemicals
  • Food product

Highlights

  • Vertical basket with top load and with bottom discharge
  • Automatic discharge with scraper knife
  • Fixed frame or GMP design available
  • Full inspection of process area is possible with the GMP design, and meets pharmaceutical industry requirements
  • Production of bulk pharmaceutical products from synthesis processes
  • Suitable for products requiring a wide filtering surface
  • No contact between the operator and the product during operation makes it suitable for toxic and flammable products
  • The centrifuge may be kept under a constant inert atmosphere
  • Rotating distributor for feeding and washing allows for uniform cake distribution and avoids vibrations

Control Options

  • Complete PLC controls with touch screen interface
  • Switch between automatic, semiautomatic, and manual operation
  • Variable frequency drive (VFD) speed control for the basket
  • Knife and cover opening are hydraulically operated
  • ATEX (Europe) electrical enclosures or NEC (North America)
  • Optional instrumentation integrated into the control system including oxygen monitoring, temperature, pressure, liquid feed flow, N2 purge flow, effluent particle detection and fluid clarity

Discharge

  • Automatic Discharge by scraper knife movement up and down, radially by steps, or total peel off (vertical peeler)
  • Nitrogen nozzles to remove heel cake internally

Cleaning

  • Its highly effective I.P. system (Clean-in- Place) uses a W.M.E. (Washing Machine Effect)and spray balls.
  • Multipurpose application: The C.I.P. system avoids cross-contamination between products from one campaign production to another, which makes the machine suitable for multi-purpose applications
  • C.I.P.
    • The centrifuge should be cleaned at every change of product to avoid cross contamination between campaign productions. The fully automated centrifuge cleaning system is composed of 2 main stages: Washing Machine Effect and cleaning with spray balls, which can be alternated to achieve maximum cleaning and to optimize the consumption of the cleaning liquid.
  • Washing Machine Effect (WME) (optional)
    • The centrifuge is filled with the washing liquid up to a predetermined height and is put in rotation. During the automatic washing sequence, the basket rotates both clockwise and counterclockwise. The knife goes in and out so that the washing liquid reaches all points of the process area, including the discharge chute. 

Machine Characteristics

  • Easily replaceable filter cloth is mounted in the basket by rings
  • High level surface finishesfor the process areas; mirror-like or electrochemical polishing are available
  • Relatively small footprint – limited horizontal space required
  • Inertia base installation with visco dampers
  • Construction materials:
    • parts in contact with the product: all stainless steels and special alloys are available, such as AISI 316L, AISI 904L, Hastelloy, Monel, ALLOY 59, 254 SMO, NICKEL, TITANIUM, SAF 2205.
    • Surface coating option: HALAR (ECTFE)
    • Elastomers: antistatic and FDA certified, Teflon ETFE, and hard rubber

Technical Services

  • Field service and technical support available
  • Mechanical and electrical parts
  • Process control and maintenance manuals
  • FDA qualification documentation and book to complete the plant
  • Certifications and construction documentation
  • Mechanical and electrical upgrades

Chemical Applications
Pharma Applications

Standard Sizes and Technical Data

Centrifuge model: TM
Unit
Basket Diameter
mm
Basket Length
mm
Filtering Surface
m2
Cake Volume
liters
Max Load
kg
Max Speed
RPM
G Factor
xg
Centrifuge Weight
kg
800/250 800 250 0.63 63 79 1650 1216 1500
800/400 800 400 1.01 100 125 1500 1006 2000
1000/500 1000 500 1.57 200 250 1200 805 3800
1000/630 1000 630 1.98 250 312 1200 805 4250
1250/700 1250 700 2.75 400 500 1000 700 6400
1250/800 1250 800 3.14 500 625 1000 700 6700
1600/800 1600 800 4.02 820 1025 900 724 12000
1600/1000 1600 1000 5.03 1025 1280 900 724 13000
1700/1190 1700 1190 6.3 1377 1721 850 686 14500
1850/1250 1850 1250 7.26 1710 2140 800 643 16500